Exons 4-7 were flanked by loxP sites and a FRT-flanked PGK-neo cassette was inserted immediately downstream of the second loxP site. Flp-mediated recombination removed the PGK-neo cassette leaving exons 4-7 floxed. (J:254695)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count