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CRISPR/Cas9 genome editing is used to modify amino acids TTV (nucleotides ACTGTGGTA) to MGK (nucleotides ATGGGCAAG) in exon 2. As part of the repair of the CRISPR cleavage, there is a 40 bp insert immediately 3' of the stop codon, which is useful for PCR genotyping. (J:275974)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
