BAC clone RP23-223G1 containing the mouse Fut1, Fut2, and Sec1 loci was manipulated through Red/ET recombination technology. In this deletion, a loxP-flanked neomycin cassette is used to replace a 30 kB region containing the coding region of Fut2 and Sec1. The BAC was also modified to contain a knockout of Fut1, Fut1tm1Dzhou (J:278494)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
Intergenic deletion, Intragenic deletion
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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