The targeting vector introduced into intron 1 a loxP site, an FRT site, splice acceptor, IRES, hygromycin resistance cassette, polyadenylation sequence, zeomycin resistance cassette, and FRT site. An additional loxP site was isnerted downstream of exon 2. Cre-mediated recombination removed the selection cassettes and exon 2. (J:258043)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(129S6/SvEvTac x C57BL/6NCrl)F1
Targeted
Insertion, Intragenic deletion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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