LoxP sites were inserted into the introns flanking exon 5 and 8, along with a neo cassette (G418 resistance) surrounded by FRT sites as a selectable marker. The neo cassette was removed via FLP-mediated recombination. (J:270119)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count