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CRISPR/Cas9 genome editing technology was used to create a deletion of sequences encoding the stalk domain, which contains all known proteolytic cleavage sites. The protein encoded by the modified allele lacks amino acids Ile133 to Ser149 and contains Arg at the former Trp150 position. (J:266262)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
