Angpt4^{tm1.1(cre)Ekl}

Using recombineering approach, targeting vector contained 1.2 and 11.4 kb genomic arms and Cre-pA-Frt-Neo-pA-Frt cassette inserted into the first exon of the Angpt4 gene was used in homologous recombination in ES cells. An Frt-flanked Neo cassette was removed by crossing with the ACTB-FLPe transgenic mouse line. (J:267502)