The targeting construct containing a Frt-flanked Neo gene, a diphtheria toxin A (DTA), and a 3xFlag-tag was used for homologous recombination in ES cells to insert the flag tag after the first methionine of the Bach2 gene. Germline transmitted mice were bred with FLPe mice to remove the neo gene. (J:272661)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
B6.Cg-Thy1a
Targeted
Insertion
--
1
3
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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