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Five serine residues in the S2053 cluster in exon 46 (S2026, S2038, S2050, S2052, S2053) were replaced with alanines and an FRT flanked neo cassette was inserted in intron 45 via homologous recombination. Flp mediated recombination removed the neo cassette. These changes prevent phosphorylation at these residues in the mutant protein. (J:276977)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
