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The conserved serine at position 2053 was mutated to an aspartic acid and an FRT flanked neo cassette was inserted in the upstream intron via homologous recombination. Flp mediated recombination removed the neo cassette. This mutation produces a protein with a phosphomimetic substitution. (J:220823)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
