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Targeting vector PG00105_W_3_A10 from the IKMC was used to generate the allele. An frt-lacZ-loxP-neo cassette-frt-loxP construct was inserted into intron 3 and a single loxP site was inserted into intron 4. Cre-mediated recombination of the loxP sites resulted in the removal of the neo cassette and exon 4 from the germline. No expression was detected in the sperm, trachea or ependyma of homozygous mutant mice at the mRNA or protein level. (J:278278)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
