Exons 4 and 5 were flanked by loxP sites and an frt-flanked neomycin selection cassette. FLP-mediated recombination removed the neomycin selection cassette in the germline. (J:264724)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count