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A neo cassette replaced 3.2 kb of Mag1 genomic DNA, including most of exon 1 together with its ATG start codon as well as its upstream promoter region. This is a null allele of all three splice isoforms. Western blotting of the kidney cortex confirmed complete loss of Magi1 protein expression in the null mice. (J:237632)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
