Exon 2 of the endogenous locus was replaced by a cDNA consisting of exons 2-16 flanked by loxP sites, followed by an internal ribosomal entry site (IRES) to enable expression of beta-galactosidase from the inserted bacterial lacZ gene. (J:241326)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count