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A transgenic cassette carrying a genomic fragment comprised of the 9.6 kb 5'-flanking region, exon 1, intron 1, and a part of exon 2 of the mouse DMP1 gene fused to human HB-EGF (DT-R) cDNA with a polyadenylation signal was used to generate transgenic mice. Lines 2 and 4 were generated. This promoter conferred preferential expression of DT-R in osteocytes, but not in osteoblasts. (J:129907)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
