Exons 1-9 were flanked by loxP sites and an frt-flanked neomycin selection cassette. The neomycin selection cassette was removed via FLP-mediated recombination in the germline. (J:277685, J:287294)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count