LoxP sites were introduced flanking exon 1 of the gene, with a neomycin cassette flanked by FRT sites used as a selectable marker. Flp-mediated excision removed the neomycin selection cassette. (J:265677)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count