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EN
A loxP_2272 site was inserted upstream of exon 2, and an FRT flanked neo cassette, a loxP site, an inverted mutated exon 2 with two serine to alanine mutations (S152A and S284A), a loxP_2272 site and a loxP site were inserted downstream of exon 2. Flp mediated recombination removed the neo cassette. Cre mediated recombination removed the wild-type exon 2 and flipped the mutant exon 2 into the correct orientation. This allele lacks the BDNF-dependent GR-phosphorylation sites in exon 2. (J:277414)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
