Two Loxp sites were inserted, flanking the coding sequences containing both the principal ATG (Based on Ntn1 cDNA sequence NM_008744) and the cryptic ATG (Based on Ntn1 cDNA: BC141294) and the alternative promoter in intron 3. In addition, a FRT-flanked Neomycin cassette was inserted in 5 to the LoxP-flanked region. FLP-mediated recombination resulted in the deletion of the loxP flanked selection cassette. (J:249067)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129
Targeted
Insertion
--
1
2
7

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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