Two Loxp sites were inserted, flanking the coding sequences containing both the principal ATG (Based on Ntn1 cDNA sequence NM_008744) and the cryptic ATG (Based on Ntn1 cDNA: BC141294) and the alternative promoter in intron 3. In addition, a FRT-flanked Neomycin cassette was inserted in 5 to the LoxP-flanked region. FLP-mediated recombination resulted in the deletion of the loxP flanked selection cassette. (J:249067)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count