LoxP sites were inserted in positions flanking exons 4 and 5. An frt-flanked neomycin selection casssette was removed via FLP-mediated recombination in the germline. (J:274150)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count