Vim^tm1Sibg

Targeted mutagenesis was used to generate mutations reslting in the substitution of Ser to Ala in the vimentin head domain of the encoded protein at multiple positions. These include codons 6, 24, 38. 46. 55. 64, 65, 71, 72, 82 and 86 in exon 1. (J:276637)