The biotin acceptor peptide (Avi) targeting cassette was inserted in frame to the terminal exon of the gene. A loxP-flanked neomycin selection cassette was removed via Cre-mediated recombination in the germline. (J:240078)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count