Mouse Grem2 is postnatally overexpressed in adult cardiomyocytes under the control of regulatory elements from the alpha-myosin heavy chain (Myh 6) promoter that is active in the adult heart. qPCR analysis of whole heart RNA samples from transgenic mice confirmed a significant increase in Grem2 expression relative to wild-type controls. (J:250034)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count