An frt-flanked neomycin selection cassette and a loxP site were inserted upstream of exon 3, and a second loxP site was inserted 5' to exon 3. The frt-flnaked neomycin selecction cassette was removed via FLP-mediated recombination. (J:249241)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count