A partial coding sequence of exon 2 of Elf5 was replaced with CreERT2-P2A-eGFP-SV40pA-Frt-Neo cassette-Frt by homologous recombination into BAC clone RP23-44A14. The Neo cassette flanked by Frt sites was deleted after FLP-mediated recombination. Six lines were generated and three lines with GFP expression in the mammary glands were kept for the initial screening. Line 2 and 5 showed strong GPF and essentially identical cre activity after tamoxifen induction. Line 2, male founder was selected for the detailed analysis. (J:277468)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Not Specified
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Insertion
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
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Year
IF
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