This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences TGTCACATCAAAATTAACAG and GAGAATACCCTGAGTGAAAG, which resulted in a 406 bp deletion beginning at Chromosome 2 position 19,235,420 bp and ending after 19,235,825 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000290542 (exon 3) and 288 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 16 and early truncation 16 amino acids later. There is a 6 bp deletion (CCTTTC) 15 bp downstream the 406 bp deletion. (J:188991)
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cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count