CRISPR/Cas9 genome editing technology was used to delete exon 4. Immunoblot analysis confirmed the absence of protein expression in bone marrow-derived macrophages (BMDMs) from homozygous mutant mice. (J:276397)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count