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The transgene construct carries two loxP sites flanking a STOP cassette upstream of an LZK-T2A-tdTomato (tdT) fusion gene, uinder the control of a chicken actin promoter. Cre-mediated excision of STOP activates LZK-T2A-tdT, leading to overexpression of LZK and the associated fluorescent reporter tdTomato. (J:260350)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
