LoxP sites were inserted into intron 1 and 3' of WT exon 2. An FRT site flanked selection cassette that was inserted was removed via subsequent Flp-mediated recombination. (J:277231)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count