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The targeting vector using bacterial artificial chromosomes (BACs) clone RP23-333M22 and RP23-354O18 was constructed by inserting a 2A-Cre cassette to replace the TGA stop codon of the P2rx2 gene. The Neo cassette flanked by SDA (self-deletion anchor) sites were removed in the cell. The vector was transfected into the C57BL/6 ES cell to establish mouse line by homologous recombination. (J:290412)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
