The transgene was designed with a 1.4 kb mouse Atoh1 3' enhancer (and a beta-globin minimal promoter) sequence upstream of an Flp sequence optimized for translation in mammalian cells (Flpo) joined to the ERT2 mutated estrogen receptor ligand-binding domain by the linker sequence from the Flpe/ERT2 cassette. Founder information and line numbers were not available. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:272495)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count