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A mouse Gdnf cDNA was cloned in-frame with the EGFP from the Pem212 clone, where human MT2A intron 1 was inserted into the EGFP coding region at nucleotide 898. The Pem promoter was then replaced by the Cathepsin L KpnI-SalI promoter/intron 1 fragment from a luciferase reporter construct. One of six characterized transgenic lines was used for further analysis. (J:260462)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
