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The targeting vector was generated to insert Frt-flanked neo selection cassette and IRES-cre into the exon 2 of the defensin alpha 4 (Defa4) gene. Resulting mice were crossed with FloO deleter to remove the neo selection cassette. Cre expression is restricted in Paneth cell in the intestines. (J:273741)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
