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The transgene contains the following components: the rat nestin promoter, sequence coding for Kusabira-Orange fluorescent protein with d4-type PEST sequence at the C-terminus, rat nestin 2nd intronic enhancer, and poly(A) signal sequences. The PEST sequence was added to increase temporal resolution (reduce the protein life-span). Four mouse lines were established and line 70 was found to represent nestin expression the most accurately and with the strongest signal. (J:248639)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
