Exon 1 was flanked by loxP sites and an FRT-flanked neomycin selection cassette was inserted downstream of the floxed exon 1. Flp-mediated recombination removed the neomycin cassette, leaving exon 1 foxed. (J:276373)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count