This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences ATAGTGAGTCTACAGTTTGG and ACTCGGCTTCAATAGATACT, which resulted in a 641 bp deletion beginning at Chromosome 10 position 89,772,175 bp and ending after 89,772,815 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000574231 (exon 4) and 549 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause early truncation after amino acid 82. (J:188991)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NJ
Endonuclease-mediated
Intragenic deletion
Not Specified
1
--
--

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
Show/Hide columns
Phenotypes

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Comparison
Al agent
Tutorials
Back to top