The targeting construct introduced into the locus a CAG promoter, a floxed stop cassette, and a the human SPHK2 sequence. Following cre-mediated recombination, the human protein is produced. (J:248835)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count