The targeting vector is designed to insert loxP sites flanking exons 1-5 of the gene, and an FRT-flanked neomycin selection cassette. Flp-mediated recombination removed the FRT-flanked neo cassette. (J:257626)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count