This allele from project TCPR0787 was generated at The Centre for Phenogenomics by electroporating Cas9 ribonucleoprotein complexes with four guide RNAs having spacer sequences of GCTATGAGTGTACCCTTGCT and AAAATTGGCATAGCCCCCAT targeting the 5' side and TCAAGCATACCTTTCAAGGT and GGTTTAATAGATCAAATGGA targeting the 3' side of exons ENSMUSE00001230146, ENSMUSE00001252442, and ENSMUSE00001304574 (exons 3-5) resulting in a 1,436-bp deletion of Chr19 from 12777799 to 12779234 (GRCm38). (J:200814)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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