This allele from project TCPR0383 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and three guide RNAs with spacer sequences of CACTTGAGCCATTTGACACG, GTTACAAAAGTTCCATGCCG, and TTATACCCCACCATGCATTC resulting in a 738 bp deletion of Chr13 from 19729115 to 19729852 (GRCm38). This mutation is predicted to cause a frameshift with the amino acid changes after residue 10 and early truncation 40 amino acids later (p.S10Ffs*42). (J:200814)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count