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EN
This allele from project TCPR259 was generated at The Centre for Phenogenomics.It was targeted by CRISPR/Cas9 nickase-mediated single-strand DNA nicks to induce double-strand breaks repaired by NHEJ causing frame-shift mutation(s) in exon 1 of Chst14. The two guides were targeted to the forward strand of Chr 2:118926702:118926721 and the reverse strand of Chr 2:118926686:118926705 (GRCm38). (J:200814)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
