This allele from project TCPR0619 was generated at The Centre for Phenogenomics by injecting Cas9 mRNA and four guide RNAs with spacer sequences of TAGGCGGGACTGTGGCACCC and CGATCTCCAACTAGGATGTG targeting the 5' side and GCCCAAACCATAGAGGTAGA and CTGGGCAAGTGAGTAACTAT targeting the 3' side of exon ENSMUSE00000396327 resulting in a 393-bp deletion of Chr12 from 112112431 to 112112823 and a 468-bp deletion of Chr12 from 112112828 to 112113295_insA (GRCm38). (J:200814)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
C57BL/6NCrl
Endonuclease-mediated
Intragenic deletion
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1
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Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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