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The targeting vector was constructed by inserting translation stop codon TAATAA into exon 2 which results in stop of translation of exon 2 therefore deleting the Ig1 domain and inserting loxP and FRT-neo-FRT-loxP cassette into exon 3 upstream and downstream, respectively. Western blot analysis indicates that only the NP55 isoform and not the NP66 isoform is expressed in the forebrain of homozygous mice. (J:276256)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
