The targeting construct is designed to insert the C terminal portion of S1pr1 fused to a C-terminal luciferase fragment (amino acids 394-550) with a polyadenylation signal, followed by a floxed neomycin resistance (neo) cassette, into the C-terminus of the S1pr1 gene. Cre-mediated recombination removed the floxed neo cassette. (J:254567)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
(C57BL/6NTac x 129S6/SvEvTac)F1
Targeted
Insertion
--
1
--
1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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