The coding region of the gene was flanked by loxP sites. A frt-flanked PGK-Neo cassette was also inserted in the coding region. Flp-mediated recombination removed the neo cassette. (J:275172)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count