The targeting vector used the gene from BAC RP24-167K18 and inserted the following elements around exon 2: a loxP site, an FRT site, a neomycin resistance gene cassette, an FRT site and a loxP site into intron 1, and a third loxP site into intron 2. The neo cassette was removed through subsequent flp-mediated recombination, leaving a conditional-ready allele with exon 2 floxed. (J:275931)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count