This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CTGTTGACTAACAATACGTA and CATTAGTTAATATACATTGG, which resulted in a 173 bp deletion beginning at Chromosome X position 114,522,276 bp and ending after 114,522,448 bp (GRCm38/mm10). This mutation deletes ENSMUSE00000295916 (exon 3) and 36 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 196 and early truncation 9 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count