This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CATTGTGGTAGGAGATCAAG and CTATCGACCCAACACACCAC, which resulted in a 431 bp deletion beginning at Chromosome 11 position 69,001,500 bp and ending after 69,001,930 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001257651 (exon 4) and 325 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 92 and early truncation 21 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count