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The human Fc Fragment of IgA Receptor (CD89) a.1 isoform in under the control of the 1.7-kb mouse Itgam (CD11b) promoter that confers high levels of expression on monocyte/macrophages. Three lines, 73, 83, and 96 were generated. The level of transgene expression is about 10-fold higher on macrophages from line 83 than the other two lines. (J:120534)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
