This allele was generated at The Jackson Laboratory by electroporating Cas9 protein and 2 guide sequences CGCAGAAATGAAGGTTATGG and TCCGAAGACTAAATCTTAAA, which resulted in a 367 bp deletion beginning at Chromosome 1 position 161,967,700 bp and ending after 161,968,066 bp (GRCm38/mm10). This mutation deletes ENSMUSE00001249072 (exon 2) and 281 bp of flanking intronic sequence including the splice acceptor and donor and is predicted to cause a change of amino acid sequence after residue 7 and early truncation 20 amino acids later. (J:188991)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count